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KMID : 0438319930020010063
Pusan Journal of Psychiatry
1993 Volume.2 No. 1 p.63 ~ p.73
A Study of the Neurophysiological Dysfunction in Alcoholics on the topographic Mapping of Cognitive Evoked Potentials



Abstract
To investigate the characteristic features of the topographic mapping of cognitive evoked potentials in alcoholics, the authors classified the alcoholics into Type 1 and Type 2 patient group according to onset age and performed the mapping of
cognitive
evoked potential to the Type 1 patients group, Type 2 patient group and normal control group. The latencies and amplitudes of the P3 were compared on 20 sites of the scalp among these 3 groups.
The amplitudes of P3 were significantly lower for the Type 2 patient group than Type 1 patient group on Fp2, F3, F4, T3, C3, Cz, C4, T4, T5, P3, Pz, P4, and O2. The latencies of P3 were significantly longer for both Type 1 and Type 2 patients
groups
than normal control group on F7, F3, Fz, T3, C3, Cz, C4, T4, T5, P3, O1, and Oz. The few lead could make difference between Type 1 and Type 2 patient groups by the latency of P3.
These results could confirm that the change of amplitude of P3 in Alcoholics was mainly due to Type 2 patient group whose decrease of amplitude of P3 was prominent and suggested the potentiality of clinical application of P3 on the diagnosis and
classification of alcoholics.
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