KMID : 0438319930020010063
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Pusan Journal of Psychiatry 1993 Volume.2 No. 1 p.63 ~ p.73
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A Study of the Neurophysiological Dysfunction in Alcoholics on the topographic Mapping of Cognitive Evoked Potentials
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Abstract
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To investigate the characteristic features of the topographic mapping of cognitive evoked potentials in alcoholics, the authors classified the alcoholics into Type 1 and Type 2 patient group according to onset age and performed the mapping of
cognitive
evoked potential to the Type 1 patients group, Type 2 patient group and normal control group. The latencies and amplitudes of the P3 were compared on 20 sites of the scalp among these 3 groups.
The amplitudes of P3 were significantly lower for the Type 2 patient group than Type 1 patient group on Fp2, F3, F4, T3, C3, Cz, C4, T4, T5, P3, Pz, P4, and O2. The latencies of P3 were significantly longer for both Type 1 and Type 2 patients
groups
than normal control group on F7, F3, Fz, T3, C3, Cz, C4, T4, T5, P3, O1, and Oz. The few lead could make difference between Type 1 and Type 2 patient groups by the latency of P3.
These results could confirm that the change of amplitude of P3 in Alcoholics was mainly due to Type 2 patient group whose decrease of amplitude of P3 was prominent and suggested the potentiality of clinical application of P3 on the diagnosis and
classification of alcoholics.
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